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My translational research provided me with the opportunity to publish peer-reviewed articles, and secure patents that cover a wide variety of biomedical & tissue engineering applications including monoclonal antibodies for breast cancer and autoimmune disorder treatments, biomedical device coatings, tissue scaffolds, drug delivery vehicles, wound dressings, packaging materials, and implants.

Peer-Reviewed Publications 

1. Hopkins, S; Pant, J; Goudie, M; Handa, H. Covalently Bound S-nitroso-N-acetylpenicillamine to Electrospun Polyacrylonitrile Nanofibers for Multifunctional Topical Healing Applications. ACS Applied Biomaterials. 3 (11), 7677-76865
2. Khairallah Atwi; Arnab Mondal; Pant, J; Zezhen Cheng; Omar El Hajj; Ifeoma Ijeli; Hitesh Handa; Rawad Saleh. Physicochemical properties and cytotoxicity of brown carbon produced under different combustion conditions. Atmospheric Environment. 2021, 244, 117881
3. Zhu L; Pearson W.D.; Benoit L. S.; Xie J; Pant J, Yang Y, Handa H, Howe Y. J.; Y C, Vidal J. E.; Maier R; and Zhao Y. Highly Efficient Antimicrobial Activity of CuxFeyOz Nanoparticles Against Important Human Pathogens. Nanomaterials. 10 (11), 2294

4. Pant, J, Mondal, A; Manuel, J; Singha, P; Mancha, J; Handa, H. H2S-Releasing Composite: A Gasotransmitter Platform for Potential Biomedical Applications. ACS Biomaterials Science & Engineering. Just Accepted. 2020, 6, 4, 2062-2071

5. Pant, J., Pedaparthi S., Hopkins S.P., Goudie MJ., Douglass M., and Handa H. Antibacterial and Cellular Response Towards a Gasotransmitter Based Hybrid Wound Dressing. ACS Biomaterials Science & Engineering, 2019, 5 (8), 4002-4012

6. Singha P., Workman CD., Pant J., Hopkins S., H Handa. Zinc‐oxide Nanoparticles Act Catalytically and Synergistically with Nitric Oxide Donors to Enhance Antimicrobial Efficacy. Journal of Biomedical Material Research Part B, 2019
7. Douglass ME., Goudie MJ., Pant J., Singha P., Hopkins Sean., Devine R., Schmiedt WC., Handa H. Catalyzed Nitric Oxide Release via Cu Nanoparticles Leads to an Increase in Antimicrobial Effects and Hemocompatibility for Short-Term Extracorporeal Circulation. ACS Applied Biomaterials. 2019, 262539-2548 8. Pant, J., Nguyen DT., Goudie M.J., Hopkins, S.P., Handa, H. Nitric Oxide Releasing Antibacterial 3D Bone Scaffolds. Journal of Biomedical Material Research Part B, 2019, 107B: 1068–1078

9. Stroganv C*., Pant J* (*Shared first author), Stoychev G., Janke A., Jehnichen D., Fery A., Handa H. 4D Biofabrication: 3D patterning using shape-changing films. Advanced Functional Materials, 2018, 1706248 (Cover page invitation)

10. Hopkins S.P., Pant J., Goudie M.J., Handa H. Achieving Long-Term Biocompatible Silicone via Covalently Immobilized S-Nitroso-N-acetylpenicillamine (SNAP) That Exhibits 4 Months of Sustained Nitric Oxide Release. ACS Applied Materials & Interfaces, 2018, 10 (30), 27316-27325

11. Grommersch B., Pant J., Hopkins S.P., Goudie M.J., Handa H. Bio-Templated Synthesis and Characterization of Mesoporous Nitric Oxide-Releasing Diatomaceous Earth Silica Particles. ACS Applied Materials & Interfaces, 2018, 10 (3), pp 2291–2301
12. Jones A., Pant J., Lee E., Goudie M.J., Gruzd A., Mansfield J., Mandal A., Sharma S., Handa H. Nitric oxide-releasing antibacterial albumin plastic for biomedical applications. Journal of Biomedical Materials Research A, 2018. (DOI: 10.1002/jbm.a.36349)

13. Pant J., Goudie M.J., Chaji S.M., Johnson B.W., Handa H. Nitric oxide-releasing vascular catheters for eradicating bacterial infection. Journal of Material Research Part B. 106B: 2849–2857

14. Goudie M.J., Pant J., Handa H. Liquid-infused nitric oxide-releasing (LINORel) silicone for decreased fouling, thrombosis, and infection of medical devices. Scientific Reports. 2017 Oct 19; 7(1):13623

15. Pant, J., Goudie, M.J., Hopkins, S.P., Brisbois, E.J., Handa, H. Tunable nitric oxide release from S-nitroso-N-acetylpenicillamine via catalytic copper nanoparticles for biomedical applications. ACS Applied Materials & Interfaces, 2017, 9 (18), pp 15254–15264

16. Pant, J., Gao J, Goudie M.J., Hopkins, S.P., Handa, H. A multi-defense strategy: Enhancing the bactericidal activity of a polymeric composite using a nitric oxide donor and surface-immobilized quaternary ammonium compound. Acta Biomaterialia, 2017, 58, 421-431

17. Singha, P., Pant, J., Goudie, M. J., Workman, C. D., & Handa, H. (2017). Enhanced antibacterial efficacy of nitricoxide-releasing thermoplastic polyurethanes with antifouling hydrophilic topcoats. Biomaterials Science, 2017, 5, 1246-1255 (Cover page)
18. Sundaram, J., Pant, J., Goudie, M. J., Mani, S., & Handa, H. (2016). Antimicrobial and Physicochemical Characterization of Biodegradable, Nitric Oxide-Releasing Nanocellulose-Chitosan Packaging Membranes. ACS Journal of Agricultural and Food Chemistry, 2016, 64(25), 5260.
19. Goudie MJ., J. Brisbois E.J., Pant J., Alex Thompson, Potkay JA, and Handa H. Characterization of an S-nitroso-N-acetylpenicillamine–based nitric oxide-releasing polymer from a translational perspective. International Journal of Polymeric Materials and Polymeric Biomaterials, 2016, 65(15) 769-778.
20. Gao, J., Huddleston, EN., White EM., Pant J., Handa, H. Locklin J. "Surface Grafted Antimicrobial Polymer Networks with High Abrasion Resistance." ACS Biomaterials Science & Engineering, 2016, 2 (7), pp 1169–1179
21. Kapur S., Gupta S., Padmavati DV, Pal A., Pant J., Rashi Jain. “Rapid sensor-based technology: A novel tool for direct Antimicrobial Susceptibility testing in Urinary Tract Infection”. Translational Medicine and Biotechnology 2014 2(1), 22-28

BOOK CHAPTER(S)

22. Pant J., Goudie MJ, Brisbois, EJ., Handa, H., “Nitric oxide-releasing polyurethanes”. Advances in Polyurethane Biomaterials, 2016, 417–449 (Book Chapter)

 

 

Patents

1. Pant J.; Jason J. Locklin; Qiaohong Liu; Priyadarshini Singha; Hitesh Handa; Marcus J. Goudie. Surfaces and Coating Compositions Having Antifouling, Antithrombotic, and Antibacterial Properties and Methods of Making. PCT/US2018/56778

2. Pant J.; Handa Hitesh. Antimicrobial compositions with wound healing properties. Serial no.: 62/682,663. Patented granted-Dec’ 2019- US10494493B1


3. Hitesh, H.; Pant, J.; Goudie, M.J.; Hopkins H., Achieving Long-term non-thrombogenic and antibacterial Silicone via Covalently Immobilized S-Nitroso-N-acetylpenicillamine (SNAP) that Exhibits 4 Months of Sustained Nitric Oxide Release

4. Pant, J.; Nguyen D.T., Handa H., Antibacterial wound treatments with clot-promoting properties. Serial no.: 62/810,634. Docket no. 222105-820. Patent granted by USPTO


5. Pant, J.; Sundaram, J.; Goudie, M.J.; Mani, S; Handa, H. Nitric oxide-releasing biodegradable polymers for food packaging applications. Patent Application Number 62/435,706. Patent granted by USPTO


6. Goudie, M.J.; Pant, J.; Handa, H. Nitric oxide-releasing slippery surfaces for medical device applications. Patent Application Number 62/336,469) 7. Grommersch, B.; Pant, J.; Goudie, MJ.; Hopkins S.; Handa, H. Handa, Hitesh, et al. "Mesoporous nitric oxide-releasing silica particles, methods of making, and uses thereof." U.S. Patent Application No. 16/051,812 (Granted)

7. Grommersch, B.; Pant, J.; Goudie, MJ.; Hopkins S.; Handa, H. Handa, Hitesh, et al. "Mesoporous nitric oxide-releasing silica particles, methods of making, and uses thereof." U.S. Patent Application No. 16/051,812 (Granted)

Presentation and Abstracts 

Publication_Jitendra%20Pant_edited.jpg

 Inhibition of bacterial adhesion on the nitric oxide-releasing surface

Biomaterials Science 5 (7), 1246-1255

 

  1.  Jitendra Pant. Postdoc 180 Competition-3 Minute Research Talk. University of Michigan. Finalist. Dec' 2020

  2. Khairallah Atwi, Jitendra Pant, Arnab Mondal, Zezhen Cheng, Omar El Hajj, Hitesh Handa, Rawad Saleh. The Cytotoxicity of Brown Carbon and its Dependence on Combustion Conditions and Light Absorption Properties. American Association for Aerosol Research. Oct’ 2019

  3. Jitendra Pant, Dr. Shanmugasundaram Natesan. Development of Nitric Oxide Releasing Bio-active Wound Dressing for Combat Burn Wound Infection Treatment. US Military Health System Research Symposium (MHSRS-19-02348 - Poster Session 2 - #085). Aug’ 2019

  4. Jitendra Pant, EJ Brisbois, MK Chug, S Hopkins, C Feit, H Handa. Reduction of biofouling and infection of indwelling medical devices via combined nitric oxide (NO) release and antifouling polymer interfaces. In Abstract of Society for Biomaterials. 2019 (Vol. 257). 1155 16th St, Nw, Washington, Dc 20036 US. March 2019

  5. Manjyot Kaur Chug, Jitendra Pant, Sean Hopkins, Megan Douglass, Corbin Feit, Hitesh Handa, Elizabeth Brisbois. Integration of antifouling and Nitric Oxide-Releasing polymer for enhanced biocompatibility of insulin cannula. In Abstracts of Papers of the American Chemical Society

  6. Megan Doughlas, Jitendra Pant, Hitesh Handa. Nitric oxide-releasing/generating polymer for clinical applications. Georgia BioInnovation Sumit, Atlanta. Oct’ 2019

  7. Jitendra Pant. Shanamurugan. Development of Nitric oxide-releasing bio-active wound dressing for combat burn wound infection treatment. Department of Defense, Texas. Sept’ 2019

  8. Elizabeth J Brisbois, Marcus J Goudie, Jitendra Pant, Hitesh Handa. Evaluation of S-nitroso-N-acetylpenicillamine (SNAP)-based polymer from a translational perspective. Oct’ 2018 Society for Biomaterials

  9.  Jitendra Pant, Hitesh Handa. The antibacterial and cellular response towards a gasotransmitter-based wound dressing. Georgia BioInnovation Sumit, Atlanta. Oct’ 2018(best poster award: Special visit by Dr. Redfield, Direct of CDC).

  10. Jitendra Pant, Hitesh Handa. Nitric oxide-releasing Wound Dressing. Biomedical Engineering Society, Atlanta. Oct’ 2018. (BMES travel award).Jitendra Pant

  11. Jitendra Pant, Hitesh Handa. Tunable release of nitric oxide from SNAP via catalytic copper to inhibit bacterial infection. Society for Biomaterials Conference. Atlanta. April 2017 (Chair’s research travel award). 

  12. Jitendra Pant, Hitesh Handa. Copper nanoparticles assisted enhanced nitric oxide release. Graduate Research Competition, University of Georgia. April 2017 (Top 3 posters by vote).

  13. Jitendra Pant, Sarah Chaji, Hitesh Handa. Innovative Nitric Oxide-Releasing Materials for Prevention of Infection in Vascular Catheters. Engineering Research Showcase, Georgia. Aug’ 2016 (Best poster award)
  14. Bioengineering Seminar, University of Georgia. Nitric oxide-releasing material. Sept’ 2017 Jitendra Pant (invited).

  15.  Artificial skin substitute for burn Injuries 3 Minute Thesis Competition Jitendra Pant. Top 3 finalists out of >100 participants university-wide). Sept’ 2016

  16. Jitendra Pant, Marcus Goudie, Hitesh Handa. Antibacterial and antithrombotic NO-releasing material for biomedical application. Biomedical Engineering Society, Minnesota (Oral Invited). Oct' 2016

  17. Jitendra Pant BITS Pilani University, India. ATMOS Technical Festival Life science and us. Jitendra Pant.  Oct’ 2013. (Best oral presentation award nationwide).

  18. Jitendra Pant. Modern Methods in Infection Biology. Winter Institute, University of Wurzburg, Germany (travel award). Sept’ 2013 (1 out of 25 scholars selected globally)

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